Vaccines for low- and middle-income countries have traditionally been procured in multi-dose containers of 10 or 20 doses. However, vaccines in single or low-dose presentations offer potential advantages such as reduced wastage and increased access that must be weighed against potential disadvantages such as higher costs and supply chain and cold chain capacity requirements. Research by the Dose Per Container Partnership in Senegal examined the relationship between dose per container (DPC) for the vaccines in the Senegalese Expanded Programme on Immunization and tradeoffs in terms of wastage, cost, coverage, timeliness, safety, health care worker behavior, and supply chain and cold chain effects.
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