The HIV field has been characterized by efforts to break through barriers to epidemic control —from innovations generated by networks of people living with HIV, to biomedical HIV-prevention tools such as pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC). With adolescent girls and young women (AGYW) as the new face of HIV in sub-Saharan Africa, the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) launched the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Partnership to focus resources and attention on HIV-prevention options for this vulnerable group. DREAMS private-sector partners (Bill & Melinda Gates Foundation, Gilead Sciences, Girl Effect, Johnson & Johnson, and ViiV Healthcare) further stimulated multi-sectoral approaches to mitigate inequitable social and gender norms, gender-based violence, and poverty, all of which exacerbate AGYW vulnerability. DREAMS Innovation Challenge, JSI 2019.
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